Autopsy report · NCT04972318

Two Different Ventilatory Strategies in Acute Respiratory Distress Syndrome Due to Community-acquired Pneumonia

“Low recruitment rate with no possibility to achieve pre specified sample size before funding ends.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 2 years 1 month before it stopped.
• 214 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Hospital do Coracao

Sponsor type

University, hospital or other

Conditions

Community-acquired Pneumonia; Acute Respiratory Distress Syndrome

Interventions

Positive end-expiratory pressure titration with driving pressure control; ARDSNet ventilatory strategy

Participants

214

Sites

6

Countries

Brazil

Trials that died the same way

• Combined CT Colonography and PET Imaging in Mantle Cell Lymphoma
  “No study recruitment due to time constraints and lack of support.” (72% match in meaning)
• Ischemia Driven Enoxaparin Therapy in ACS Presenting as Low Risk (IDEAL)
  “Low rate of patient recruitment. Cannot achieve sample size.” (71% match in meaning)
• Microbiome in Colorectal Cancer Onset and Progression
  “Recruitment rate was too low to continue the study.” (71% match in meaning)
• Bright by Three (BB3) Effectiveness Study
  “Lack of funding to recruit target sample size” (70% match in meaning)
• Efficacy of Medical Therapy in Women and Men With Angina and Myocardial Bridging
  “Low recruitment, insufficient funding” (70% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.