Autopsy report · NCT04820621

Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment

“This study is prematurely terminated due to changes in sponsor's overall development strategy. The decision of termination is not related to any safety concern of the compound.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 3 months before it stopped.
• 5 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

Bayer

Sponsor type

Industry

Conditions

Chronic Kidney Disease

Interventions

Runcaciguat (BAY1101042)

Participants

5

Sites

1

Countries

Germany

Trials that died the same way

• Study to Investigate Comparative Efficacy, Safety and Immunogenicity Between AVT16 and Entyvio
  “The study has been terminated based on Sponsor decision. This decision is not related to any safety concerns associated with the investigational products. It is related to the fact that study will be not required for product dossier submission.” (76% match in meaning)
• A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Immunogenicity of LB4330 in Patients With Advanced Solid Tumors（MEETCD8-001）
  “Due to adjustments in the sponsor's development strategy, it has been decided to terminate the study.” (75% match in meaning)
• A Phase II Study of Envofolimab and BD0801 With/Without Chemotherapy in Patients With Advanced Solid Tumors
  “The study was terminated due to the sponsor's research and development strategy adjustment.” (75% match in meaning)
• An Evaluation of the Erchonia Laser As a Non-Invasive Treatment to Improve the Appearance of Skin Laxity
  “The study was terminated early due to sponsor decision unrelated to safety or efficacy findings” (75% match in meaning)
• Safety and Pharmacodynamics of SHR-1707 in Alzheimer's Disease Patients
  “Based on the adjustment of the sponsor's R\&D strategy, it is decided to terminate this study in advance.” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.