Autopsy report · NCT04802837

Safety, Tolerability and the Pharmacokinetics of Ridinilazole in Adolescent Subjects

“SMT19969-C006 study was terminated in alignment with corporate decision to pursue further development of drug candidate with a partner.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 1 year 4 months before it stopped.
• 2 participants enrolled.
• Results were posted on the registry 11 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Summit Therapeutics

Sponsor type

Industry

Conditions

Clostridioides Difficile Infection

Interventions

Ridinilazole; Vancomycin

Participants

2

Sites

18

Countries

United States

Trials that died the same way

• Cvac as Maintenance Treatment in Patients With Epithelial Ovarian Cancer in Complete Remission Following First-line Chemotherapy or Second-line Treatment
  “The study was terminated due to company restructuring and changes in drug development priorities.” (72% match in meaning)
• A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-Alcoholic Steatohepatitis
  “The study was terminated due to strategic business reasons.” (68% match in meaning)
• Panobinostat/Velcade in Multiple Myeloma
  “This study was terminated because the drug company stopped making the study drug” (67% match in meaning)
• TQB3909 Tablets in Subjects With Relapsed or Refractory Mantle Cell Lymphoma (MCL)
  “Study terminated for strategic business reasons” (67% match in meaning)
• A Safety Study of PF-08046045/SGN-35T in Adults With Advanced Cancers
  “Study terminated as part of strategic considerations” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.