Autopsy report · NCT04755244

A Study of Evorpacept (ALX148) With Venetoclax and Azacitidine for Acute Myeloid Leukemia (ASPEN-05)

“While intended to be a Phase 1/2 clinical study, the study never moved forward to Phase 2.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 2 years 3 months before it stopped.
• 14 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

ALX Oncology Inc.

Sponsor type

Industry

Conditions

Acute Myeloid Leukemia; AML, Adult

Interventions

evorpacept; venetoclax; azacitidine

Participants

14

Sites

5

Countries

United States

Trials that died the same way

• The Biophysical Impact of Transcutaneous Spinal Cord Stimulation Within a Single Session
  “The study was never initiated because of lack of funding and research priorities have been shifted elsewhere.” (70% match in meaning)
• Venetoclax and Quizartinib in Treating Patients With FLT3-mutated Recurrent or Refractory Acute Myeloid Leukemia
  “This study was terminated early due to other competing trials, therefore did not go on to the Phase II portion of the study.” (68% match in meaning)
• Computer-Based Program to Facilitate Readiness and Motivation for Smoking Cessation
  “Due to staff changes the study never started.” (68% match in meaning)
• Five Fraction SABR Dose Escalation for Early Stage Squamous Cell Carcinoma of the Lung
  “After completion of Phase I, it was decided not to initiate Phase II of the study.” (67% match in meaning)
• Needle-X: Usability Testing of a Smartphone Application
  “The study was never started by the responsible party (medical student who is no longer at the institution).” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.