Autopsy report · NCT04688658

Duvelisib in Combination With Nivolumab in Patients With Advanced Unresectable Melanoma

“Secura Bio, Inc. discontinued support of the trial.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 9 months before it started.
• Ran for about 3 years 4 months before it stopped.
• 13 participants enrolled.
• Results were posted on the registry 11 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

John Kirkwood

Sponsor type

University, hospital or other

Conditions

Unresectable Melanoma

Interventions

Nivolumab; Duvelisib

Participants

13

Sites

1

Countries

United States

Trials that died the same way

• Evaluation of MST-188 in Acute Lower Limb Ischemia
  “Program discontinued to persue alternate indications.” (61% match in meaning)
• Phase 3 Trial to Evaluate the Efficacy and Safety of DKP21102_B Added on to DKP21102_A Compared With DKP21102_A
  “The clinical trial was withdrawn due to a commercial decision.” (61% match in meaning)
• A Study to Evaluate the Efficacy and Safety of Liso-cel Compared to Standard of Care in Adults With Relapsed or Refractory Follicular Lymphoma
  “Replaced with another clinical trial.” (61% match in meaning)
• RNA Extraction and Amplification From Biopsy Specimens in Subjects With Metastatic Renal Cell Carcinoma (AGS-NTS-017)
  “The sponsor's clinical program for the agent used in this study was discontinued.” (60% match in meaning)
• Surface EMG Biofeedback for Children With Cerebral Palsy
  “The PI for this trial, which has been terminated, is no longer employed by USC. After repeated attempts of contact, we are unable to identify the PI's current employment. We would therefore request close out of this clinical trial record.” (60% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.