Autopsy report · NCT04651764

Transanal Resection of Rectal Lesions With the ColubrisMX ELS System

“Terminated by ColubrisMX due to its identification of irregularities in the conduct of the trial (not related to clinical safety or effectiveness of the device)”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month after it had already started.
• Ran for about 9 months before it stopped.
• 26 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

ColubrisMX

Sponsor type

Industry

Conditions

Rectal Adenoma; Rectal Polyp; Rectal Lesion

Interventions

ColubrisMX Endoluminal Surgical (ELS) System

Participants

26

Sites

3

Countries

United States

Trials that died the same way

• Neoadjuvant Lu-PSMA Radioligand Therapy and Ipilimumab in Men With Very High-risk Prostate Cancer
  “The clinical trial has been terminated due to the revocation of funding. Although one subject was enrolled, the participant withdrew prior to receiving any treatment. No trial-related procedures generating evaluable clinical data were performed.” (71% match in meaning)
• To Assess the Safety, Tolerability and Pharmacokinetics of ACH-000029 in Healthy Subjects
  “Based on the unblinded clinical data, the trial was terminated.” (70% match in meaning)
• Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers
  “The study was terminated due to the sponsor's decision to discontinue the clinical trial.” (69% match in meaning)
• Study to Determine the Safety and Efficacy of INCB018424 in Patients With Polycythemia Vera or Essential Thrombocythemia
  “Termination of the clinical trial by sponsor.” (68% match in meaning)
• Avelumab and Radiation in Muscle-Invasive Bladder Cancer
  “In agreement with the drug sponsor and the institution, the trial has been terminated due to slow accrual.” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.