Autopsy report · NCT04604132

Derazantinib Alone or in Combination With Paclitaxel, Ramucirumab or Atezolizumab in Gastric Adenocarcinoma

“Terminated prematurely for administrative reasons not related to patient safety.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 2 years 1 month before it stopped.
• 47 participants enrolled.
• Results were posted on the registry 1 year 4 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Basilea Pharmaceutica

Sponsor type

Industry

Conditions

Gastric Adenocarcinoma

Interventions

Derazantinib; Derazantinib-paclitaxel-ramucirumab combination; Derazantinib-paclitaxel-ramucirumab combination; Derazantinib; Derazantinib

Participants

47

Sites

81

Countries

Argentina, Australia, Belgium, Brazil, Chile, France, Germany, Italy, Poland, Russia, South Korea, Spain and more

Trials that died the same way

• Safety and Efficacy of Buprenorphine Transdermal System (BTDS) in Subjects With Moderate to Severe Osteoarthritis Pain
  “terminated early for administrative reasons unrelated to safety or efficacy” (79% match in meaning)
• Comparing the Efficacy of Two Oral Rehydration Solutions, With or Without the Probiotic Lactobacillus Reuteri DSM 17938 and Zinc, on the Duration and Severity of Acute Gastroenteritis in 6 - 36 Months Old Children in Out-patient Care
  “Terminated due to lack of eligible patients.” (77% match in meaning)
• Ph 1B B-701 in Combination With Pembrolizumab in Metastatic Transitional Cell Carcinoma of the Urothelial Tract
  “Terminated due to safety concerns.” (73% match in meaning)
• Modulating Repetitive Negative Thinking Related Brain Networks in Young Adults With Depression
  “Terminated due to PI resignation. Not related to safety, efficacy, or administrative mandate.” (72% match in meaning)
• Efficacy and Safety of Salkera Emollient Foam in the Treatment of Moderate to Severe Keratosis Pilaris, a Prospective Study
  “terminated due to administrative reasons.” (71% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.