Autopsy report · NCT04347941

Awake Prone Positioning to Reduce Invasive VEntilation in COVID-19 Induced Acute Respiratory failurE

“Enrollment for trial was terminated on January 26, 2021 after a third interim analysis demonstrated that a pre-defined statistical criteria for efficacy were met as part of meta-trial study of awake prone positioning.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 6 months before it stopped.
• 24 participants enrolled.
• Results were posted on the registry 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

University College Hospital Galway

Sponsor type

University, hospital or other

Conditions

ARDS, Human; Mechanical Ventilation Complication; COVID19

Interventions

Prone Positioning; Standard of care.

Participants

24

Sites

1

Countries

Ireland

Trials that died the same way

• Stop Exogenous Allergic Alveolitis (EAA) in Childhood
  “After several years of recruitment only 4 patients were included. Study timelines for study completition too long. Decided to terminate trial.” (62% match in meaning)
• Evaluation of the Clinical and Economic Impact of painPRIMER in the Treatment of Low Back Pain in a Primary Care Setting
  “The study was terminated on 02-Jun-2014 due to slow enrollment. The study was not terminated for reasons of either safety or efficacy.” (62% match in meaning)
• Phase II Study of TAEST16001 in Soft Tissue Sarcoma
  “The study was terminated due to initiation of a new clinical trial with an updated study design.” (61% match in meaning)
• PSMA-PET/CT Registry
  “Not due to a safety concern; terminated early due to changing clinical trial landscape at centre” (61% match in meaning)
• Evaluation of the Clinical Benefit of a Transmitter for Contralateral Routing of Signals (CROS)
  “This clinical trial has been early terminated due to recruiting issues of the calculated sample size.” (61% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.