Autopsy report · NCT04262193

Dual-Orexin Antagonism As a Mechanism for Improving Sleep and Drug Abstinence in Opioid Use Disorder

“Did not meet enrollment goals.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 year before it started.
• Ran for about 3 years 6 months before it stopped.
• 37 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Wayne State University

Sponsor type

University, hospital or other

Conditions

Opioid-use Disorder; Sleep

Interventions

Suvorexant; Suvorexant Placebo

Participants

37

Sites

1

Countries

United States

Trials that died the same way

• Comminuted Intra-Articular Distal Tibia Fracture Fixation Using Computer Techniques
  “Enrollment goal was not met.” (92% match in meaning)
• Metastatic Colorectal Cancer: Treatment Response With Dynamic Contrast MRI
  “Study did not meet enrollment goals.” (90% match in meaning)
• Evaluation of Culture Negative Severe Acute Respiratory Infection in Mexico
  “Enrollment goal could not be met.” (87% match in meaning)
• Vitamin D Deficiency and Atopic Dermatitis
  “Not meeting enrollment goals.” (84% match in meaning)
• Hearing Resources and Outcomes in the Emergency Department (HERO-ED)
  “Did not meet enrollment” (83% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.