Autopsy report · NCT04000919

Effects of 5HTP and LDOPA on CNS Excitability After SCI

“PI left UofL and intends to reopen study at University of Alberta”

The sponsor’s own words in the registry.

Life of this trial

• Suspended: paused, and may or may not restart.
• 30 participants planned (an estimate, not an actual count).

Vital statistics

Status

Suspended

Phase

Phase 2, Phase 3

Sponsor

Jessica M D'Amico

Sponsor type

University, hospital or other

Conditions

Spinal Cord Injuries

Interventions

5HTP; L-DOPA; Placebo oral tablet; Carbidopa

Participants

30 (planned, not actual)

Sites

1

Countries

United States

Trials that died the same way

• Assessment of Primary and Metastatic Brain Tumor Hypoxia With Fluoromisonidazole, FDG and Water
  “PI retired, study closed” (67% match in meaning)
• Randomized Controlled Trial (RCT) Umbilical Hernia Repair (UHR) Absorbable vs Non-absorbable Synthetic Mesh
  “study was never opened and PI now leaving institution” (67% match in meaning)
• Noninvasive Cardiac Output Measurements in Patients With Pulmonary Hypertension Undergoing Right Heart Catheterization With Acute Vasodilator Testing
  “The PI closed this study and went to another institution.” (67% match in meaning)
• RCT of SPG Blocks for Post-dural Headache
  “Both Study PI's left the institution” (65% match in meaning)
• Quality Control: A Prospective Analysis of EVD Effectiveness
  “PI left institution prior to study completion” (65% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.