Autopsy report · NCT03970616
A Study of Tivozanib in Combination With Durvalumab in Subjects With Advanced Hepatocellular Carcinoma
Cause of deathSlow enrollment, also regulatory or ethics
“The study was terminated due to regulatory approval of newer therapeutic options and slower than anticipated accrual.”
Life of this trial
- Registered 4 months before it started.
- Ran for about 3 years 6 months before it stopped.
- 27 participants enrolled.
- No results are posted on the registry.
Vital statistics
- Status
- Terminated
- Phase
- Phase 1, Phase 2
- Sponsor
- AVEO Pharmaceuticals, Inc.
- Sponsor type
- Industry
- Conditions
- Hepatocellular Carcinoma
- Interventions
- Tivozanib; Durvalumab
- Participants
- 27
- Sites
- 10
- Countries
- United States
Trials that died the same way
- Safety and Efficacy of MAGE-A3/A6 T Cell Receptor Engineered T Cells (KITE-718) in HLA-DPB1*04:01 Positive Adults With Advanced Cancers
“The study was terminated due to the sponsor's decision to discontinue the clinical trial.” - Evaluation of the Clinical and Economic Impact of painPRIMER in the Treatment of Low Back Pain in a Primary Care Setting
“The study was terminated on 02-Jun-2014 due to slow enrollment. The study was not terminated for reasons of either safety or efficacy.” - A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer
“Study terminated due to various reasons impacting the feasibility of future clinical development” - Study of Magrolimab Combinations in Patients With Relapsed/Refractory Multiple Myeloma
“This study was terminated early due to the Sponsor's decision to discontinue development of the investigational drug and close the program.” - A Long Term Safety Study of Mavrilimumab in Adult Subjects With Rheumatoid Arthritis
“The study was terminated after approximately 3 years due to future clinical development plans, including ethical considerations.”
Look deeper
- The official registry record (the source of truth)
- Record history: every change the sponsor made
- Open it in the database
Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.