Autopsy report · NCT03940690

Interest of Intravitreal Injections of Anti-VEGF as Initial and Adjuvant Treatment in Coats Disease

“Study futility based on the interim analysis”

The sponsor’s own words in the registry.

Life of this trial

• Registered 6 months before it started.
• Ran for about 4 years before it stopped.
• 18 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Fondation Ophtalmologique Adolphe de Rothschild

Sponsor type

University, hospital or other

Conditions

Retinal Telangiectasis; Coats Disease

Interventions

Anti-VEGF injections of bevacizumab; Laser

Participants

18

Sites

6

Countries

France

Trials that died the same way

• Study of M5049 in DM and PM Participants (NEPTUNIA)
  “Based on interim analyses for futility” (89% match in meaning)
• Efficacy and Safety Study of DP-b99 in Treating Acute Ischemic Stroke
  “The result of a pre-planned interim futility analysis” (86% match in meaning)
• Bivalirudin Infusion for Ventricular Infarction Limitation
  “Futility at the interim analysis.” (85% match in meaning)
• Perioperative Treprostinil in Pediatric Patients Undergoing the Fontan Operation
  “Interim futility analysis” (84% match in meaning)
• Tissue Adhesive vs. Sterile Strips After Cesarean Delivery
  “Based on results of an interim analysis, the study was halted for futility” (84% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.