Autopsy report · NCT03843918

A Study on the Safety and Efficacy of LAE001 in the Treatment of Metastatic Prostate Cancer

“This is phase I/II study, phase I study completed, phase II study started and enrolled 1 patient. Company strategy consideration to terminated phase 2 study finally.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 4 years 6 months before it stopped.
• 33 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Laekna Limited

Sponsor type

Industry

Conditions

Prostate Cancer Metastatic

Interventions

LAE001

Participants

33

Sites

2

Countries

China

Trials that died the same way

• Safety and Efficacy of 4 Investigational HSV 2 Vaccines in Adults With Recurrent Genital Herpes Caused by HSV 2
  “business reasons-Phase 2/Part B not conducted. Study terminated after last patient enrolled in Phase 1/Part A” (81% match in meaning)
• Imatinib in Combination With Dacarbazine and Capecitabine in Medullary Thyroid Carcinoma
  “Study closed following Phase I portion, insufficient activity to continue to Phase II.” (72% match in meaning)
• Reparixin in COVID-19 Pneumonia - Efficacy and Safety
  “The sponsor has decided to start with a separate protocol for phase 3 and therefore this study was terminated with only phase 2.” (71% match in meaning)
• Safety, Pharmacokinetics and Efficacy Study of QCC374 in PAH Patients
  “Study was terminated early for strategic reasons. Only Part I of the study was completed.” (70% match in meaning)
• BI-1607 in Combination with Trastuzumab in Subjects with HER2-positive Advanced Solid Tumors
  “After the completion of phase IA, for business reasons it was decided to terminate the study.” (70% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.