Autopsy report · NCT03631979

Intestinal Lavage to Promote Enteral Feeding and Prevent Necrotizing Enterocolitis in Extremely Preterm Infants

“Recruitment was terminated early because of staffing limitations affecting delivery of the intervention, expiration of study funding, and slower-than-anticipated recruitment, which made completion of the planned sample size infeasible.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 6 years 9 months before it stopped.
• 200 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Uppsala County Council, Sweden

Sponsor type

Government (non-US federal)

Conditions

Necrotizing Enterocolitis; Time to Full Enteral Nutrition

Interventions

Intestinal lavage with normal saline

Participants

200

Sites

1

Countries

Sweden

Trials that died the same way

• Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary Sclerosis
  “Early termination due to operational feasibility reasons, resulting from a slow recruitment rate and logistical and financial difficulties that prevent reaching the planned sample size within the study schedule.” (81% match in meaning)
• Evaluation of the Abbott i-STAT TBI Biomarker Test
  “Study was terminated early due to recruitment limitations and available funding for continued recruitment and follow up” (76% match in meaning)
• Comparison of the Performance of ICM and CIED in Detecting AF
  “Recruitment to study was insufficient. This was despite extending the recruitment period. Decision taken to terminate study due to lack of recruitment.” (75% match in meaning)
• Improving Surgical Safety of Seniors Through Preoperative Cognitive Screening
  “This study was terminated prior to its planned enrollment due to low recruitment rates at the time that the funding for the study was completed.” (74% match in meaning)
• Safety, Tolerability and Pharmacodynamics of AP214 Acetate in Patients Undergoing Cardiac Surgery
  “The study was terminated due to a considerably lower recruitment rate than anticipated” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.