Autopsy report · NCT03339336

Efficacy and Safety Study of BIIB074 in Participants With Small Fiber Neuropathy

“Sponsor decision to close study early; not due to safety concerns”

The sponsor’s own words in the registry.

Life of this trial

• Registered 7 months before it started.
• Ran for about 2 years 10 months before it stopped.
• 265 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Biogen

Sponsor type

Industry

Conditions

Small Fiber Neuropathy; Diabetes Mellitus

Interventions

BIIB074; Placebo

Participants

265

Sites

97

Countries

Bulgaria, Canada, Czechia, Denmark, France, Germany, Greece, Hungary, Italy, Netherlands, Poland, Spain and more

Trials that died the same way

• A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary
  “Sponsor Decision to close study” (88% match in meaning)
• Hero: A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics (PK) and Pharmacodynamics (PD) of ION269 in Participants With Down Syndrome (DS) at Risk for Alzheimer's Disease (AD)
  “Sponsor decision to terminate study early. Decision not based on safety concerns.” (88% match in meaning)
• ML29255 Neoadjuvant Vemurafenib and Cobimetinib Melanoma
  “Sponsor has decided to close study.” (84% match in meaning)
• Combo of Cabozantinib With Abiraterone in Chemotherapy-Naïve Subjects With Bone-Metastatic CRPC
  “Sponsor decided to close the study prior to completion of enrollment. This was a business decision and not based on the safety results of the study.” (84% match in meaning)
• Selinexor and Lenalidomide for Consolidation and Maintenance Treatment in Multiple Myeloma Post-transplant
  “Study sponsor decided to close study.” (82% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.