Autopsy report · NCT03303911

A Pharmacokinetic and Pharmacodynamic Evaluation of Cytisine in Healthy Smokers

“It has been difficult to recruit participants meeting study entry criteria that are \>65 years of age and not for any safety reasons.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year before it stopped.
• 26 participants enrolled.
• Results were posted on the registry 1 year 1 month after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Achieve Life Sciences

Sponsor type

Industry

Conditions

Smoking Cessation

Interventions

Cytisine

Participants

26

Sites

1

Countries

United Kingdom

Trials that died the same way

• Relativity Study Between Idiopathic Ventricular Arrhythmia and Sex Hormone Levels in Different Stages of Menstrual Cycle
  “it's difficult to recruit enough participants eligible for this study” (69% match in meaning)
• A Trial of Oral Nutritional Supplements on Nutritional Status and Clinical Outcomes
  “difficulty in recruiting elderly subjects” (68% match in meaning)
• Incidence and Characteristics of Postoperative Cognitive Dysfunction in Elderly Quebec Francophone Patients
  “Elderly population difficult to recruit” (67% match in meaning)
• Exercise Therapy for Asthma (ETA Trial)
  “Study proved difficult to recruit” (65% match in meaning)
• Effects and Consequences for Mother and Child From Treatment for Depression
  “Difficulties in recruiting participants.” (64% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.