Autopsy report · NCT03191201

A Double Blind Randomised Placebo-controlled Trial to Assess the Role of Iron Repletion in Glucose Homeostasis.

“The reason for early termination is difficulties recruiting that caused a premature ending of financial resources ensuring protected time for research.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 2 years 9 months before it stopped.
• 32 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Prof Gérard WAEBER

Sponsor type

University, hospital or other

Conditions

Iron-deficiency; Iron Toxicity; Glucose Metabolism Disorders (Including Diabetes Mellitus); Metabolic Side Effects of Drugs; Metabolic Disorder, Glucose; Safety Issues

Interventions

Ferric Carboxymaltose; 0.9% sodium chloride solution

Participants

32

Sites

1

Countries

Switzerland

Trials that died the same way

• Safety and Efficacy of Melatonin in Patients With Multiple Progressive Primary Sclerosis
  “Early termination due to operational feasibility reasons, resulting from a slow recruitment rate and logistical and financial difficulties that prevent reaching the planned sample size within the study schedule.” (74% match in meaning)
• Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss
  “Early study termination occurred due to inability to secure funding” (74% match in meaning)
• Safety, Tolerability and Efficacy of AVP-786 for the Treatment of Disinhibition
  “The study was terminated prematurely because of difficulty with recruiting.” (70% match in meaning)
• Observational Biologic or Prosthetic Mesh
  “Premature termination due to cease of funding” (67% match in meaning)
• Paracetamol Versus Placebo in Conjunction With Strong Opioids for Cancer Pain
  “Funding was terminated early due to slow recruitment.” (66% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.