Autopsy report · NCT03070574

Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome

“Due to poor patient recruitment and insufficient financing.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 9 months before it started.
• Ran for about 1 year 5 months before it stopped.
• 8 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Christoph Gasche

Sponsor type

University, hospital or other

Conditions

Colorectal Cancer

Interventions

mesalamine 2400 MG (5-ASA); mesalamine 1200 MG; Placebo

Participants

8

Sites

6

Countries

Austria, Germany, Israel, Netherlands, Poland, Sweden

Trials that died the same way

• Trial Comparing Intravesical Cocktail With Intravesical Dimethyl Sulfoxide (DMSO) in Painful Bladder Syndrome/Interstitial Cystitis (PBS/IC)
  “Poor recruitment, poor patient compliance, lack of funding” (88% match in meaning)
• Evaluation of Compliance With Management of Acute Coronary Syndrome on Discharge From Cardiac Intensive Care
  “due to poor patient recruitment” (87% match in meaning)
• The Risk of Intraventricular Hemorrhage With Flat Midline Versus Right-Tilted Flat Lateral Head Positions
  “Due to low patient recruitment” (83% match in meaning)
• TRAUMA HELP: Healing and Analgesia With Propranolol
  “Lack of eligible patient recruits/feasibility considerations.” (79% match in meaning)
• The CAPTAIN Trial: Cerebrolysin Asian Pacific Trial in Acute Brain Injury and Neurorecovery
  “Poor patient recruitment” (77% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.