Autopsy report · NCT02989597

Intraoperative Methadone Administration for Improved Pain Control in Spinal Fusion Patients

“Due to personnel loss and logistical issues the study was unable to be completed as planned.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 8 months before it started.
• Ran for about 3 years 3 months before it stopped.
• 10 participants enrolled.
• Results were posted on the registry 2 years 5 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Montefiore Medical Center

Sponsor type

University, hospital or other

Conditions

Pain, Postoperative

Interventions

Methadone Hydrochloride; Standard pain regimen; Spinal Fusion Surgery; Dexamethasone; Ketamine; Remifentanil

Participants

10

Sites

1

Countries

United States

Trials that died the same way

• Use of EndoFLIP and Manometry Prior to G-POEM
  “Unable to complete study procedures due to staffing issues.” (75% match in meaning)
• Intranasal Challenge of Healthy Adults With Respiratory Syncytial Virus (RSV)
  “The study was terminated as it was determined to not be feasible to complete enrollment and the study within the required timeline and budget.” (75% match in meaning)
• Neoadjuvant Chemotherapy Plus Nephroureterectomy for Locally Advanced Upper Tract Transitional Cell Cancer
  “Study was unable to recruit subjects meeting the study requirements.” (74% match in meaning)
• 24-hour IOP Fluctuation Profile Recorded With SENSIMED Triggerfish in Primary Open-angle Glaucoma (POAG) Patients After Cataract Surgery
  “Due to staff departures we were unable to execute this study” (74% match in meaning)
• Erwinase for Patients With Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) (IND 104224)
  “Study was terminated due to lack of accrual.” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.