Autopsy report · NCT02936102

A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

“The early termination was based on a business decision that FAZ053 would no longer be formulated and was not a consequence of any safety concern.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 8 years 1 month before it stopped.
• 154 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

Novartis Pharmaceuticals

Sponsor type

Industry

Conditions

Advanced Solid Tumors; Triple Negative Breast Cancer; Chordoma and Alveolar Soft Part Sarcoma

Interventions

FAZ053; PDR001

Participants

154

Sites

12

Countries

Canada, France, Israel, Italy, Japan, Singapore, Spain, Taiwan, United States

Trials that died the same way

• An Evaluation Of PF-03715455 In Moderate To Severe Uncontrolled Asthma
  “The termination was due to business reasons. No safety or efficacy concerns contributed to the termination of the study” (63% match in meaning)
• A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors
  “The trial was terminated for strategic reasons. The decision was not based on any safety and/or efficacy concerns.” (59% match in meaning)
• Study of Inlexisertib (DCC-3116) in Participants With RAS/MAPK Pathway Mutant Solid Tumors
  “Trial terminated due to business decision, not based on any safety or efficacy concerns.” (59% match in meaning)
• Study of the Efficacy and Safety of Parsaclisib in Participants With Primary Warm Autoimmune Hemolytic Anemia
  “A business decision was made to discontinue further enrollment. There were no safety concerns that contributed to this decision.” (59% match in meaning)
• Merotocin in Mothers With Inadequate Milk Production and Infants Delivered Prematurely
  “The trial was prematurely terminated. Termination was not because of safety concerns but due to slow recruitment.” (57% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.