Autopsy report · NCT02774291

Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes

“Due to lack of accrual the study was formally terminated on 01-JUL-2020. Primary Completion and Study Completion Dates have been revised based accordingly based on respective definitions”

The sponsor’s own words in the registry.

Life of this trial

• Registered 11 months before it started.
• Ran for about 3 years 3 months before it stopped.
• 3 participants enrolled.
• Results were posted on the registry 3 years after it ended.

Vital statistics

Status

Terminated

Phase

Early Phase 1

Sponsor

Albert Einstein College of Medicine

Sponsor type

University, hospital or other

Conditions

HLA-A2 Positive Cells Present; Metastatic Malignant Neoplasm; Metastatic Malignant Neoplasm in the Brain

Interventions

Aldesleukin; Anti-thyroglobulin mTCR-transduced Autologous Peripheral Blood Lymphocytes; Cyclophosphamide; Filgrastim; Fludarabine Phosphate; Laboratory Biomarker Analysis

Participants

3

Sites

1

Countries

United States

Trials that died the same way

• Safety, Pharmacokinetics and Efficacy Study of QCC374 in PAH Patients
  “Study was terminated early for strategic reasons. Only Part I of the study was completed.” (78% match in meaning)
• Intracoronary Bolus Only Compared With Intravenous Bolus and 12-hours Infusion of Abciximab in Non-ST Elevation Myocardial Infarction.
  “The study was terminated early due to a shortage of research and analytical personnel, which prevented the completion of the study as planned” (78% match in meaning)
• Dehydroepiandrosterone (DHEA) and Letrozole in Treating Patients With Metastatic Breast Cancer
  “Study was terminated due to lack of accrual” (78% match in meaning)
• Therapeutic Exercise in Patients With Hemophilia
  “The Study was terminated due to lack of funding for continuing” (77% match in meaning)
• LMB-100 Followed by Pembrolizumab in the Treatment of Adults With Mesothelin-Expressing Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
  “Study was terminated due to slow accrual.” (77% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.