Autopsy report · NCT02762253

Study of the Safety and Effectiveness of Photochemically Induced Collagen Cross-Linking in Eyes With Keratoconus.

“No IND submitted to the FDA”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 years 8 months after it had already started.
• Ran for about 3 years 7 months before it stopped.
• 320 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Nvision Laser Eye Centers

Sponsor type

Industry

Conditions

Keratoconus

Interventions

Riboflavin drops

Participants

320

Sites

11

Countries

United States

Trials that died the same way

• Chloroquine (CQ) and Azithromycin (AZ) Combination for Malaria Prophylaxis
  “The IND has been withdrawn from FDA” (84% match in meaning)
• Perceval S Aortic Heart Valve Study- North America
  “FDA approval” (69% match in meaning)
• Electrical Impedence Tomography With ENLIGHT2100
  “Device received FDA approval” (68% match in meaning)
• Iontophoresis in Psoriasis
  “FDA did not provide approval of the use of the drug for the study” (68% match in meaning)
• The Use of Autologous Mesenchymal Stem Cell Preparation for Treatment of Refractory Migraine
  “Pending FDA approval” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.