Autopsy report · NCT02532010

Pacritinib Combined With Decitabine or Cytarabine in Older Patients With AML

“The study was put on clinical hold by the sponsor since Feb 9th 2016, and was later decided not to re-open due to financial constraints.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 2 years 4 months before it stopped.
• 13 participants enrolled.
• Results were posted on the registry 8 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Weill Medical College of Cornell University

Sponsor type

University, hospital or other

Conditions

Acute Myeloid Leukemia (AML)

Interventions

Pacritinib; Decitabine; Cytarabine

Participants

13

Sites

1

Countries

United States

Trials that died the same way

• AZD1222 Vaccine for the Prevention of COVID-19
  “The study was put on hold in September 2020 due to a safety concern in another trial but never restarted. In the meantime our clinical development program now includes a similar study with a different design, which we prefer to complete now.” (79% match in meaning)
• Study of Melflufen (Melphalan Flufenamide) in Combination With Daratumumab in Relapsed-Refractory Multiple Myeloma
  “The sponsor decided to terminate the study due to financial issues following an FDA request for a partial clinical hold.” (76% match in meaning)
• A Study of Obinutuzumab in Combination With CHOP Chemotherapy Versus Rituximab With CHOP in Participants With CD20-Positive Diffuse Large B-Cell Lymphoma (GOYA)
  “The study was closed by the Sponsor according to the protocol-specified minimum post-treatment follow-up period of 3 years.” (76% match in meaning)
• Pembrolizumab Plus Lenvatinib in Previously Treated Classic Kaposi Sarcoma
  “The lack of adequate funding has made it impossible to continue with the clinical study As this study was not initiated, no subject was included and no data was collected,thus no result can be obtained SPONSOR\_DECISION End of trial date:15 Oct 2025” (75% match in meaning)
• UK Baby Study Using a Baby Wash and Lotion Regimen
  “The study has been on hold due to the COVID-19 pandemic. As of Mar 23, 2022, the Sponsor has decided to terminate the study for administrative reasons.” (75% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.