Autopsy report · NCT02473562

Varenicline Treatment for Excessive Daytime Sleepiness in Parkinson's Disease

“insufficient patient enrollment, insufficient funds for completion”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 years 1 month after it had already started.
• Ran for about 4 years 8 months before it stopped.
• 22 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Amsterdam UMC, location VUmc

Sponsor type

University, hospital or other

Conditions

Parkinson's Disease

Interventions

Varenicline; Placebo (for varenicline)

Participants

22

Sites

2

Countries

Netherlands

Trials that died the same way

• Human Brain Adaptation to Chronic Pain and Its Effects on Opioid Use
  “Insufficient patient enrollment.” (87% match in meaning)
• Medical Therapies for Chronic Post-Traumatic Headaches
  “inadequate enrollment, insufficient funds to continue enrollment” (85% match in meaning)
• Early Biomarkers of Tumor Response in High Dose Hypofractionated Radiotherapy Word Package 3 : Immune Response
  “Lack of patient enrollment” (80% match in meaning)
• Intravitreal Dexamethasone Implant (Ozurdex) Versus Bevacizumab in Patients With Diabetic Macular Edema Undergoing Cataract Surgery
  “Inadequate patient enrollment” (77% match in meaning)
• Vitamine D Treatment in Chronic Heart Failure
  “financial reasons / insufficient enrollment activity” (77% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.