Autopsy report · NCT02460367

Immunotherapy Combination Study in Advanced Previously Treated Non-Small Cell Lung Cancer

“Lack of enrollment and changing landscape of standard of care.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 8 months before it started.
• Ran for about 5 years before it stopped.
• 16 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

NewLink Genetics Corporation

Sponsor type

Industry

Conditions

Non-small Cell Lung Cancer; Progression of Non-small Cell Lung Cancer; Non-small Cell Lung Cancer Recurrent

Interventions

Docetaxel; Tergenpumatucel-L; Indoximod

Participants

16

Sites

2

Countries

United States

Trials that died the same way

• Outpatient Treatment of Gram Positive Wound Infections in the Diabetic Foot: A Pharmaco-economic Comparison of Daptomycin vs. Vancomycin Based Regimens
  “Lack of patient enrollment” (73% match in meaning)
• Study of Eribulin Mesylate in Combination With PEGylated Recombinant Human Hyaluronidase (PEGPH20) Versus Eribulin Mesylate Alone in Subjects With Human Epidermal Growth Factor Receptor 2 (HER2)-Negative, High-Hyaluronan (HA) Metastatic Breast Cancer (MBC)
  “evolving standard of care and difficulties of enrolling participants” (72% match in meaning)
• Efficacy of a Home-Based Exercise Program for Heart Failure
  “Lack of enrollment. Difficult to obtain Physician approval.” (71% match in meaning)
• Effect of Vorinostat on ACTH Producing Pituitary Adenomas in Cushing s Disease
  “Lack of enrollment.” (70% match in meaning)
• Intravitreal Dexamethasone Implant (Ozurdex) Versus Bevacizumab in Patients With Diabetic Macular Edema Undergoing Cataract Surgery
  “Inadequate patient enrollment” (70% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.