Autopsy report · NCT02433392

Study of Intraparenchymal Therapy as Adjunct Therapy in Patients With Recurrent, Resectable Glioblastoma Multiforme.

“The decision to terminate the trial was based on the slow rate of recruitment across the programme of studies”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 years 4 months after it had already started.
• Ran for about 3 years 7 months before it stopped.
• 9 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

Boston Scientific Corporation

Sponsor type

Industry

Conditions

Glioma

Interventions

CM-BC2

Participants

9

Sites

1

Countries

United Kingdom

Trials that died the same way

• A Study of Plitidepsin in Patients With Relapsed or Refractory Angioimmunoblastic T-cell Lymphoma
  “The main reason that motivated the study termination was the slow recruitment of the trial.” (84% match in meaning)
• Effects of Upper Extremity Rehabilitation Using Smart Glove in Stroke Patients
  “The trial was prematurely terminated due to slow recruitment.” (82% match in meaning)
• Imatinib for Cytomegalovirus Prophylaxis and Treatment After Allogeneic Hematopoietic Stem Cell Transplantation
  “The trial is terminated due to the extremely low recruitment rate.” (81% match in meaning)
• Stop Exogenous Allergic Alveolitis (EAA) in Childhood
  “After several years of recruitment only 4 patients were included. Study timelines for study completition too long. Decided to terminate trial.” (80% match in meaning)
• Endoscopic Full Thickness Resection of Gastric Subepithelial Tumors (FROST)
  “According to study protocol the trial was terminated because the recruitment of trial participants was insufficient.” (78% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.