Autopsy report · NCT01944982

Salvage Therapy With Chemotherapy and Natural Killer Cells in Relapsed/Refractory Paediatric T Cell Lymphoblastic Leukaemia and Lymphoma

“The low recruitment rate makes it very difficult to complete the study within a reasonable period of time.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 3 years 2 months before it stopped.
• 7 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Hospital Infantil Universitario Niño Jesús, Madrid, Spain

Sponsor type

University, hospital or other

Conditions

Relapsed/Refractory Paediatric T Cell Lymphoblastic Leukaemia and Lymphoma

Interventions

Expanded haploidentical natural killer cells (NKAEs)

Participants

7

Sites

1

Countries

Spain

Trials that died the same way

• The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders
  “Study not feasible - very low recruitment rate” (81% match in meaning)
• Exercise Therapy for Asthma (ETA Trial)
  “Study proved difficult to recruit” (75% match in meaning)
• Microbiome in Colorectal Cancer Onset and Progression
  “Recruitment rate was too low to continue the study.” (74% match in meaning)
• Pharmacotherapy for Alcohol Dependence in Convicted Drinking Drivers
  “Recruitment proved to be extremely difficult.” (73% match in meaning)
• Calcium, Vitamin D and Metformin to Treat Insulin Resistance in Obese African American Adolescent Females
  “Poor recruitment to the study” (72% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.