Autopsy report · NCT01868620

Non-inferiority Trial of Iontophoretic Corneal Collagen Crosslinking (CXL) Compared to Standard Corneal Collagen Crosslinking in Progressive Keratoconus.

“The investigator decided to stop the trial due to a lack of inclusion.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 3 years 10 months before it stopped.
• 28 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

University Hospital, Toulouse

Sponsor type

University, hospital or other

Conditions

Progressive Keratoconus

Interventions

Iontophoretic CXL; Standard CXL

Participants

28

Sites

1

Countries

France

Trials that died the same way

• Impact of Molecular Testing on Improved Diagnosis, Treatment and Management of CAP
  “The trial was stopped earlier than planned after an ad hoc interim analysis” (73% match in meaning)
• Adverse Events of MRI With Abandoned Leads
  “The study was stopped due to challenges with recruitment and insufficient insurance coverage for the required procedures, which prevented continuation of the trial.” (71% match in meaning)
• A Study to Learn About the Study Medicine (Nirmatrelvir Plus Ritonavir) in Pregnant Women With COVID-19
  “The trial prematurely terminated due to the inability to recruit the planned number of subjects. The decision to terminate the trial was not based on any safety concerns.” (70% match in meaning)
• Endoscopic Full Thickness Resection of Gastric Subepithelial Tumors (FROST)
  “According to study protocol the trial was terminated because the recruitment of trial participants was insufficient.” (69% match in meaning)
• A Study to Test the Effects of Nezavist at Different Doses in Healthy Adults
  “The trial was terminated early due to regulatory constraints preventing the continuation of study conduct.” (69% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.