Autopsy report · NCT01708265

The Dutch Asymptomatic Mitral Regurgitation Trial

“low inclusion rate”

The sponsor’s own words in the registry.

Life of this trial

• Registered 4 months before it started.
• Ran for about 8 years before it stopped.
• 12 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

UMC Utrecht

Sponsor type

University, hospital or other

Conditions

Heart; Disease, Mitral(Valve); Diseases of Mitral Valve; Mitral Valve Insufficiency

Interventions

Watchful waiting; Early mitral valve repair

Participants

12

Sites

4

Countries

Netherlands

Trials that died the same way

• Risk of Rupture of Aneurysms of the Thoracic Ascending Aorta (ATA) From the Dynamic Imaging
  “low inclusion rates” (97% match in meaning)
• PET / CT With 18F-FDG: Does it Optimize the I 123-MIBG Imaging Results in the Search for Discriminating Factors for the Implementation of an Implantable Defibrillator?
  “Inclusion rate too slow / infeasible.” (86% match in meaning)
• Video-Assisted Thoracoscopic Pulmonary Vein Isolation Versus Percutaneous Catheter Ablation in Atrial Fibrillation Trial
  “Inclusion rate insufficient” (86% match in meaning)
• Respiratory Variations for Assessing Blood Withdrawal 2
  “insufficient inclusion rate” (85% match in meaning)
• Dexmedetomidine Pharmacokinetics-pharmacodynamics in Mechanically Ventilated Children With Single-organ Respiratory Failure
  “Poor inclusion rate.” (85% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.