Autopsy report · NCT01675050

A Placebo-controlled Crossover Trial Using Cyproheptadine To Treat Children With Functional Abdominal Pain

“Due to the wide availability of the drug in clinical practice, it was impossible to recruit adequate numbers for scientific power.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year before it stopped.
• 4 participants enrolled.
• Results were posted on the registry 3 years 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

University of Michigan

Sponsor type

University, hospital or other

Conditions

Functional Abdominal Pain

Interventions

Cyproheptadine; sugar pill

Participants

4

Sites

1

Countries

United States

Trials that died the same way

• Non-invasive Improvement of Buttocks With Magnetic Device
  “It wasn't possible to recruit the desired number of patients.” (67% match in meaning)
• Phase II Trial for Patients With Loco-Regional Esophageal Carcinoma
  “The study was unable the accrue the required number of patients within a reasonable time.” (66% match in meaning)
• Intravenous Zoledronic Acid for the Treatment of Osteoporosis and Osteonecrosis in Children With Leukemia: A Pilot Study
  “While the clinical need for and the scientific merit remain valid, this regulated drug trial was not feasible logistically due to limited funds.” (65% match in meaning)
• Effects of a Supplement Derived From Palm Oil on Cholesterol Levels and Chinese Red Yeast Rice in the Blood
  “We were unable to procure the supplement for this study.” (63% match in meaning)
• Oral Medications for the Management of Acute Migraine Headache in the Emergency Department
  “The project proved not feasible to launch at Health Sciences North.” (63% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.