Autopsy report · NCT01666132

METHOD - Bone Marrow Derived Mononuclear Cells in Chronic Ischemic Disease

“Due to the slow recruitment process and the progress of newer cell types we decided to stop the trial after the phase 1 (after 10 patients included)”

The sponsor’s own words in the registry.

Life of this trial

• Registered 5 months after it had already started.
• Ran for about 4 years 3 months before it stopped.
• 10 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

Cardiocentro Ticino

Sponsor type

University, hospital or other

Conditions

Chronic Ischemic Heart Disease

Interventions

intramyocardial injection of BM cells; intramyocardial / intracoronary injection of BM cells; Best medical therapy

Participants

10

Sites

1

Countries

Switzerland

Trials that died the same way

• Effect of Citalopram on Chest Pain in Patients With Functional Chest Pain
  “The clinical trial has ended prematurely due to low patient recruitment” (67% match in meaning)
• Dose Dense Therapy and Bevacizumab in Solid Tumors and Colorectal Cancer
  “Trial did not move to Phase II portion due to poor tolerance of treatment” (67% match in meaning)
• An Efficacy, Safety, Tolerability and Pharmacokinetics Study of 12 Weeks Treatment With Simeprevir and Daclatasvir in Participants With Chronic Hepatitis C Virus Genotype 1b or 4 Infection and Either Severe Renal Impairment or End-stage Renal Disease on Hemodialysis.
  “Trial has been cancelled due to availability of new therapeutic options for patient population” (65% match in meaning)
• Study of a Melanoma Vaccine in Stage IIb, IIc, and III Melanoma Patients
  “After interim analysis the study was halted to redesign a pivotal trial.” (64% match in meaning)
• Stop Exogenous Allergic Alveolitis (EAA) in Childhood
  “After several years of recruitment only 4 patients were included. Study timelines for study completition too long. Decided to terminate trial.” (64% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.