Autopsy report · NCT01645124
Large-scale Trial Testing the Intensity of CYTOreductive Therapy in Polycythemia Vera (PV)
Cause of deathSlow enrollment, also futility
“Low accrual rate not allowing planned sample size leads to a futility condition”
Life of this trial
- Registered 4 years 2 months after it had already started.
- Ran for about 4 years 2 months before it stopped.
- 365 participants enrolled.
- No results are posted on the registry.
Vital statistics
- Status
- Terminated
- Phase
- Phase 3
- Sponsor
- Consorzio Mario Negri Sud
- Sponsor type
- University, hospital or other
- Conditions
- Polycythemia Vera
- Interventions
- Hydroxyurea; Phlebotomy
- Participants
- 365
- Sites
- 26
- Countries
- Italy
Trials that died the same way
- Feasibility and Potential Effectiveness of a Case Management Intervention for Alcohol Use-Related Problems in Frequent Users of an Emergency Department: a Pilot Study
“Insufficient accrual rate to achieve expected sample size.” - Effectiveness of a Case Management Intervention for Alcohol Use-Related Problems in Frequent Users of an Emergency Department
“Insufficient accrual rate to achieve expected sample size in the context of a global pandemic.” - A B-D-Glucan Driven Antifungal Stewardship Approach for Invasive Candidiasis
“Insufficient rate of accrual due to the start of a concomitant similar study” - Pressure Enabled Drug Delivery By Pancreatic Retrograde Venous Infusion For Advanced Pancreatic Carcinoma
“Insufficient accrual rate” - Pharmacology of Aminophylline for Acute Kidney Injury in Neonates
“insufficient rate of accrual”
Look deeper
- The official registry record (the source of truth)
- Record history: every change the sponsor made
- Open it in the database
Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.