Autopsy report · NCT01634360

Long-Term Safety, Tolerability and Efficacy in Perampanel Treated Parkinson's Disease Patients With Motor Fluctuations

“Due to termination of clinical program for Parkinson's Disease”

The sponsor’s own words in the registry.

Life of this trial

• Registered 7 years 8 months after it had already started.
• Ran for about 3 years 7 months before it stopped.
• 185 participants enrolled.
• Results were posted on the registry 4 years 8 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Eisai Inc.

Sponsor type

Industry

Conditions

Parkinson's Disease

Interventions

Perampanel

Participants

185

Trials that died the same way

• Novel Shoe Device NUSHU to Measure Gait Analysis in Parkinson's Patients
  “Enrollment goals of subjects with Parkinson's disease have been met, and the study has had difficulty enrolling control, non-PD subjects. The study has suspended recruitment while the research team evaluates the best plan going forward.” (70% match in meaning)
• Online Cognitive Training in PD, MS and Depressed Patients Treated With Electroconvulsive Therapy
  “All Parkinson's disease patients have finished training. The MS and ECT groups have not finished as these groups had trouble including 20 patients.” (63% match in meaning)
• A Phase 1 Clinical Study of NXP800 in Subjects With Advanced Cancers and Expansion in Subjects With Ovarian Cancer
  “Study terminated due to various reasons impacting the feasibility of future clinical development” (57% match in meaning)
• Alvimopan Use in Polytraumatized Patients
  “This study was terminated due to failure to enroll, a low volume of patients met criteria.” (56% match in meaning)
• QUILT-3.031: AMG 337 in Subjects With Advanced or Metastatic Clear Cell Sarcoma
  “Prematurely terminated due to lack of therapeutic effect” (56% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.