Autopsy report · NCT01632020

Effect of Metformin on Biomarkers of Colorectal Tumor Cell Growth

“Inadequate accrual”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 2 years 5 months before it stopped.
• 7 participants enrolled.
• Results were posted on the registry 1 year 6 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

University of Arkansas

Sponsor type

University, hospital or other

Conditions

Colorectal Neoplasms

Interventions

Placebo; Metformin

Participants

7

Sites

2

Countries

United States

Trials that died the same way

• Dexamethasone in Reducing Everolimus-Induced Oral Stomatitis in Patients With Cancer
  “Severe lack of accrual” (90% match in meaning)
• Calcium and Magnesium in Preventing Peripheral Neuropathy Caused by Ixabepilone in Patients With Breast Cancer
  “lack of accrual” (90% match in meaning)
• Copaíba-based Mouthwash in Oral Mucotitis Prevention and Treatment in Oral Cancer Patients During Radioteraphy
  “Poor accrual” (89% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.