Autopsy report · NCT01580215

Long Term Follow up Investigation of Endobronchial Valves in Emphysema

“Inability to reach desired recruitment goal; Sponsor executed other RCTs”

The sponsor’s own words in the registry.

Life of this trial

• Registered 3 months before it started.
• Ran for about 4 years 2 months before it stopped.
• 628 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Sponsor

Pulmonx International Sàrl

Sponsor type

Industry

Conditions

Pulmonary Emphysema

Interventions

Zephyr Endobronchial Valve (EBV)

Participants

628

Sites

1

Countries

Germany

Trials that died the same way

• Randomized Placebo Controlled Trial of IVIg in Glycine Receptor Antibody Positive Stiff-person Syndrome
  “Recruitment did not meet sponsors timeline” (65% match in meaning)
• High-Dose Vitamin D Induction in Optic Neuritis
  “inability to meet recruitment goals” (62% match in meaning)
• Enabling Family Physicians to Reduce Vaccine Hesitancy and Increase Covid-19 Vaccine Uptake
  “Unable to recruit enough sample size for the RCT” (61% match in meaning)
• Dronedarone Pattern of Use in Patients Scheduled for Elective Cardioversion (ELECTRA)
  “'Sponsor decision following recruitment issues, not related to any safety concerns in the study” (61% match in meaning)
• Ovarian Aging in Low Grade Glioma (LGG) Treated With Temozolomide
  “Low recruitment, sponsor withdrew funding.” (61% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.