Autopsy report · NCT01538251

Efficacy, Safety and Tolerability of Propionyl-L-Carnitine Hydrochloride in Patients With Mild Ulcerative Colitis

“Evidence of very low probability to success. No safety issues.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 1 year 8 months before it stopped.
• 147 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

sigma-tau i.f.r. S.p.A.

Sponsor type

Industry

Conditions

Ulcerative Colitis

Interventions

Propionyl-L-Carnitine; Placebo

Participants

147

Sites

58

Countries

Belgium, Czechia, Israel, Italy, Netherlands, Romania, Russia, Slovakia

Trials that died the same way

• Safety and Tolerability of ABM-1310 in Patients With Advanced Solid Tumors
  “Not related to safety concerns or lack of efficacy” (63% match in meaning)
• Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)
  “Lack of Efficacy, no safety concern.” (59% match in meaning)
• Efficacy and Safety of Azilsartan Medoxomil Used in Combination With Metformin in Participants With Hypertension and Diabetes
  “Business Decision; No Safety Or Efficacy Concerns. (See below)” (57% match in meaning)
• Evaluation of Alcon Ladarvision Wavefront-Guided PRK
  “Lack of resources and not because of any concern with the safety or effectiveness of the procedures studied.” (55% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.