Autopsy report · NCT01254721

A Comparison of the Effectiveness of Seroquel XR and Seroquel XR Plus Lithium in Patients With Acute Bipolar Mania: An Open-label, Randomized, Parallel Groups, Rater-blinded, 4 Week, Multicenter, Comparative,Study

“Difficulty of recruitment.”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year 10 months before it stopped.
• 131 participants enrolled.
• Results were posted on the registry 1 year 7 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

AstraZeneca

Sponsor type

Industry

Conditions

Acute Bipolar Mania

Interventions

Quetiapine fumarate; lithium

Participants

131

Sites

5

Countries

South Korea

Trials that died the same way

• Alzheimer Disease : Rehabilitation's Intervention at Home
  “difficulties of recruitment” (95% match in meaning)
• Sensitivity of Frequent SARS-CoV-2 (COVID-19) Rapid Antigen Testing Regimen
  “Difficulty with recruitment.” (95% match in meaning)
• Efficacy of Angiographic Embolization vs Non-embolization of Moderate/Poor Vascularized Vertebral Metastases on Intraoperative Bleeding During Surgery Decompression and Vertebral Stabilization.
  “Difficulties in recruitment.” (95% match in meaning)
• Failed Endometrial Ablation Treatment With Implantable Progesterone (FEAT) Study
  “Difficulty in Recruitment” (94% match in meaning)
• Phase III Efficacy and Tolerability Trial of the Fixed Dose Combination of Etodolac 400 mg and Cyclobenzaprine 10 mg Versus Isolated Active Substances in Pain Control After Impacted Third Molar Extraction
  “recruitment difficulty” (94% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.