Autopsy report · NCT01018810

A Study for Adults With Plaque Psoriasis

“The trial was terminated for several reasons, including complexities in development of LY2525623, but not because of safety concerns”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 8 months before it stopped.
• 8 participants enrolled.
• Results were posted on the registry 10 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Eli Lilly and Company

Sponsor type

Industry

Conditions

Psoriasis

Interventions

LY2525623 Intravenous; LY2525623 Subcutaneous; Placebo Intravenous; Placebo Subcutaneous

Participants

8

Sites

28

Countries

Canada, United States

Trials that died the same way

• Study of the Combination of Binimetinib and Encorafenib in Adolescent Patients With Unresectable or Metastatic BRAF V600-mutant Melanoma
  “The trial was terminated early on 05 October 2022 due to non-feasibility and poor recruitment and not based on safety concerns.” (64% match in meaning)
• A Dose Escalation Study to Assess the Safety and Tolerability of HMPL-453 in Patients With Advanced Solid Malignancies
  “The study was terminated on 23AUG2018 for safety reasons.” (62% match in meaning)
• Merotocin in Mothers With Inadequate Milk Production and Infants Delivered Prematurely
  “The trial was prematurely terminated. Termination was not because of safety concerns but due to slow recruitment.” (59% match in meaning)
• A Study to Learn About the Study Medicine Called PF-08046031 in Advanced Melanoma and Other Solid Tumors
  “The trial was terminated for strategic reasons. The decision was not based on any safety and/or efficacy concerns.” (59% match in meaning)
• Pilot Study of Denosumab in BRCA1/2 Mutation Carriers Scheduled for Risk-Reducing Salpingo-Oophorectomy
  “it was decided that due to lack of accrual on the trial, and low potential for accruing over the near future, the trial will be shut down.” (58% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.