Autopsy report · NCT00981929

Development of Cocktail for Measuring the Activity of Important Cytochrome P450 Enzymes

“Unexpected non-serious adverse events”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 1 year 4 months before it stopped.
• 412 participants planned (an estimate, not an actual count).
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

University of Southern Denmark

Sponsor type

University, hospital or other

Conditions

Cytochrome P450 Phenotype and Genotype Metrics

Interventions

Tramadol; Omeprazole, losartan, caffeine; Tramadol, omeprazole, losartan, caffeine

Participants

412 (planned, not actual)

Sites

1

Countries

Denmark

Trials that died the same way

• Collagenase Clostridium Histolyticum for Refractory Iatrogenic Esophageal Strictures
  “unexpected serious adverse event” (95% match in meaning)
• Safety and Bioactivity of AXT107 in Subjects With Diabetic Macular Edema
  “Adverse Events” (82% match in meaning)
• Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid Leukemia
  “Other - Adverse Events” (80% match in meaning)
• Short Versus Long Interval to Ileostomy Reversal After Ileal Pouch Surgery
  “Adverse Event” (77% match in meaning)
• "Watch and Wait" After Neo-adjuvant Chemoradiotherapy for Primary Locally Advanced Rectal Cancer.
  “Suspicion of adverse events” (76% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.