Autopsy report · NCT00949988

A Study of Dasatinib and Rituximab for Relapsed/Refractory Chronic Lymphocytic Leukemia

“Three subjects were enrolled and all three subjects withdrew.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 2 years 11 months before it stopped.
• 3 participants enrolled.
• Results were posted on the registry 7 years 4 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 1, Phase 2

Sponsor

University of California, San Diego

Sponsor type

University, hospital or other

Conditions

Chronic Lymphocytic Leukemia

Interventions

Dasatinib and Rituximab

Participants

3

Sites

1

Countries

United States

Trials that died the same way

• Factors Predicting Response to Shunting in Normal Pressure Hydrocephalus
  “Funding was withdrawn as number of subjects enrolled did not meet expectation” (68% match in meaning)
• Evaluation of Safety and Efficacy of the EndoLift Liver Retractor
  “The study was terminated. Six subjects were consented \& all were withdrawn before any study activities took place.” (68% match in meaning)
• Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension
  “Failure to enroll a suitable number of qualified subjects.” (67% match in meaning)
• High Versus Low Bicarbonate Bath in Critically-ill Patients Receiving Continuous Renal Replacement Therapy
  “Due to the fact that we were unable to find subjects who met all inclusion and exclusion criteria it was determined to withdraw this study.” (67% match in meaning)
• Sirolimus for the Treatment of Hyperinsulinism
  “Due to strict inclusion and exclusion criteria no subjects were enrolled” (67% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.