Autopsy report · NCT00865878

ALA-PDT Versus Vehicle PDT for Treatment of AK and Reduction of New NMSC in Solid Organ Transplant Recipients

“Orphan Drug Designation for this indication not granted”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months before it started.
• Ran for about 2 years 4 months before it stopped.
• 6 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

DUSA Pharmaceuticals, Inc.

Sponsor type

Industry

Conditions

Actinic Keratoses; Skin Neoplasms

Interventions

Aminolevulinic Acid; Vehicle

Participants

6

Sites

7

Countries

United States

Trials that died the same way

• A Post-marketing Surveillance Study on Erbitux in Combination With Platinum-based Chemotherapy in Metastatic/Recurrent Squamous Cell Cancer of the Head and Neck
  “After loss of orphan drug status in Korea, study was withdrawn due to Regulatory Authority request. Patients will be enrolled into NCT01075828 instead.” (65% match in meaning)
• Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics
  “Manufacturer discontinued drug before any participants could be enrolled.” (61% match in meaning)
• BAFF/IL-17 Bispecific Antibody Treatment in Subjects With Primary Sjogren's Syndrome
  “Drug unavailable” (57% match in meaning)
• A Randomized, Placebo-controlled, Double-blind Phase 2 Study With OSI-906 in Patients With Advanced HCC
  “Company decided not to pursue the development of this drug in this patient population at this time” (57% match in meaning)
• TGR-1202 (Umbralisib) in Treatment Naïve Patients With Chronic Lymphocytic Leukemia (CLL)
  “Drug no longer available” (57% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.