Autopsy report · NCT00745030

Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism

“Low subject recruitment and enrollment.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 months after it had already started.
• Ran for about 1 year 6 months before it stopped.
• 3 participants enrolled.
• Results were posted on the registry 11 months after it ended.

Vital statistics

Status

Terminated

Phase

Na

Sponsor

Northwestern University

Sponsor type

University, hospital or other

Conditions

REM Behavior Disorder; Parkinsonism

Interventions

Rozerem; Placebo

Participants

3

Sites

1

Countries

United States

Trials that died the same way

• Vaginal Dehydroepiandrosterone (DHEA) in Postmenopausal Breast Cancer Survivors on Aromatase Inhibitors
  “Low recruitment/enrollment” (88% match in meaning)
• CytID Analysis of Oral Lesions
  “low subject recruitment” (87% match in meaning)
• Effectiveness Study of Santyl Ointment to Treat Pressure Ulcers
  “Low enrollment of qualified subjects” (80% match in meaning)
• Results of Tc99m-Maraciclatide Scintigraphy in Subjects With Diabetes Mellitus and Heart Failure With Preserved Left Ventricular Ejection Fraction
  “Lack of Subject Recruitment” (78% match in meaning)
• Cord Milking Impacts Neurodevelopmental Outcomes in Very Low Birth Weight Infants
  “Subject recruitment and enrollment was low throughout the three years the study was active.” (78% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.