Autopsy report · NCT00636324

Level of Continuous Positive Airway Pressure (CPAP) in Preterm Infants After Extubation (L-CPAP Study)

“Difficulties in recruitment - will require longer time to achieve sample size”

The sponsor’s own words in the registry.

Life of this trial

• Registered 8 months after it had already started.
• Ran for about 2 years 11 months before it stopped.
• 23 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2

Sponsor

Hamilton Health Sciences Corporation

Sponsor type

University, hospital or other

Conditions

Respiratory Insufficiency of Prematurity

Interventions

Nasal CPAP, level 7 to 9 cmH2O; Nasal CPAP, level 4 to 6 cmH2O

Participants

23

Trials that died the same way

• The Effect of Episiotomy on Maternal and Fetal Outcomes (EPITRIAL)
  “Slower than expected recruitment rate, and larger than expected required sample.” (75% match in meaning)
• Serum-derived Bovine Immunoglobulin Effect on Mucositis
  “Recruitment slower than anticipated” (74% match in meaning)
• Ischemia Driven Enoxaparin Therapy in ACS Presenting as Low Risk (IDEAL)
  “Low rate of patient recruitment. Cannot achieve sample size.” (74% match in meaning)
• Optimizing Clinical Outcomes in Patients Undergoing Mitral Transcatheter Edge-to-edge Repair (M-TEER) for Severe Functional Mitral Regurgitation Towards Improved Guideline-directed Medical Therapy
  “Recruitment too slow” (74% match in meaning)
• Return to Work and Living Healthy After Head and Neck Cancer
  “insufficient recruitment rate” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.