Autopsy report · NCT00592566

Desmopressin and Dexamethasone Adjunctive Treatment for Leptospirosis

“Numbe of eligible patients has been decreased over time.”

The sponsor’s own words in the registry.

Life of this trial

• Registered 4 years 6 months after it had already started.
• Ran for about 3 years 3 months before it stopped.
• 64 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 2, Phase 3

Sponsor

Mahidol University

Sponsor type

University, hospital or other

Conditions

Leptospirosis

Interventions

Dexamethasone, desmopressin

Participants

64

Sites

1

Countries

Thailand

Trials that died the same way

• Optimal Surgical Treatment Of Fulminant Clostridium Difficile Colitis
  “Numer of eligible patients markedly decreased since the initiation of the study.” (68% match in meaning)
• COVidIVERmectin: Ivermectin for Treatment of Covid-19
  “Incidence has dramatically dropped and there is lack of eligible patients” (61% match in meaning)
• A Pilot Study of the Efficacy and Safety of Dupilumab Versus Placebo in Patients With Netherton Syndrome
  “no more patients corresponding to the criteriae” (60% match in meaning)
• Endothelial Protection in Convalescent COVID-19 Patients
  “Lack of the eligible patients” (58% match in meaning)
• Serial Evaluation of Drug-Eluting Stents Using OCT (STRUT-OCT)
  “Lack of eligible patients” (58% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.