Autopsy report · NCT00441363

Efficacy and Safety of Cycloset® Compared With Placebo When Added to Metformin

“Failure to Recruit in a Timely manner”

The sponsor’s own words in the registry.

Life of this trial

• Registered 2 years after it had already started.
• Ran for about 1 year 1 month before it stopped.
• 66 participants enrolled.
• Results were posted on the registry 10 years 2 months after it ended.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

VeroScience

Sponsor type

Industry

Conditions

Type 2 Diabetes

Interventions

Bromocriptine Mesylate

Participants

66

Trials that died the same way

• Influence of an Inverse Pressure Ramp in Long-term Non-invasive Ventilation on Dyspnea in the Morning After Therapy
  “Insufficient recruitment in a timely manner” (82% match in meaning)
• Assessment of GRASP Medical Device to Improve Arm Coordination After Stroke
  “failure to recruit” (82% match in meaning)
• The Efficacy of Probiotic Compared With Placebo Commitment Therapy for Treatment of Major Depressive Disorder
  “Fail to recruit” (79% match in meaning)
• Comparison of 2 Different Positional Therapies for Positional Obstructive Sleep Apnea Syndrome
  “difficulties to recruit” (75% match in meaning)
• Evaluation of the Versamed iVent in the Transport of Patients Receiving Mechanical Ventilation
  “Unable to recruit adequately” (74% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.