Autopsy report · NCT00376259

Study of Combination Therapy With LdT Plus Adefovir Versus Adefovir Alone

“The study was not completed as planned and was terminated early with agreement from the European Medicines Agency (EMEA)”

The sponsor’s own words in the registry.

Life of this trial

• Registered 4 months before it started.
• 43 participants enrolled.
• Results were posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

Novartis

Sponsor type

Industry

Conditions

Hepatitis B

Interventions

telbivudine; adefovir dipivoxil

Participants

43

Sites

6

Countries

Hong Kong, South Korea, Taiwan, Thailand, United States

Trials that died the same way

• Phase II Study of TPA Plus Dexamethasone & CMT in Hematologic Malignancies
  “Study was terminated early due to lack of experimental medication (supply issues)” (75% match in meaning)
• Panobinostat/Velcade in Multiple Myeloma
  “This study was terminated because the drug company stopped making the study drug” (75% match in meaning)
• Phase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal Cancer
  “The study was terminated because we were not able to obtain the study drug.” (73% match in meaning)
• Intracoronary Bolus Only Compared With Intravenous Bolus and 12-hours Infusion of Abciximab in Non-ST Elevation Myocardial Infarction.
  “The study was terminated early due to a shortage of research and analytical personnel, which prevented the completion of the study as planned” (73% match in meaning)
• Study of Magrolimab Combinations in Patients With Relapsed/Refractory Multiple Myeloma
  “This study was terminated early due to the Sponsor's decision to discontinue development of the investigational drug and close the program.” (72% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.