Autopsy report · NCT00286988

Topiramate for the Prophylactic Treatment of Cyclic Vomiting Syndrome in Children

“Insufficient potential subjects”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 month before it started.
• Ran for about 1 year 3 months before it stopped.
• 12 participants planned (an estimate, not an actual count).
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Monarch Medical Research

Sponsor type

University, hospital or other

Conditions

Vomiting

Interventions

Topiramate

Participants

12 (planned, not actual)

Sites

1

Countries

United States

Trials that died the same way

• Effectiveness of Dry Needling of the Sternocleidomastoid in Patients With Cervicogenic Headaches
  “Not enough viable subjects” (78% match in meaning)
• Modified Functional Magnetic Stimulation Treatment for Constipation Improvement
  “no sufficient subjects” (74% match in meaning)
• Acitretin Plasma Levels Under Hemodialysis
  “lack of subjects” (74% match in meaning)
• Intravitreal Bevacizumab vs.Combination Therapy for CNV Due to Other Than AMD
  “Lack of eligible subjects.” (70% match in meaning)
• Prospective Evaluation of Symptom Resolution in Acid Versus Non-acid Reflux Disease Following Anti-reflux Surgery
  “Unable to recruit a sufficient number of subjects.” (70% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.