Autopsy report · NCT00272870

Treatment of Newly Diagnosed Brain Tumors With Chemotherapy and Radiation Using Cells Modified for Chemoprotection and an Experimental Drug to Decrease the Tumor Cell Resistance to Chemotherapy

“Slow accrual; drug availability”

The sponsor’s own words in the registry.

Life of this trial

• Ran for about 6 years 8 months before it stopped.
• 1 participant enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 1

Sponsor

Children's Hospital Medical Center, Cincinnati

Sponsor type

University, hospital or other

Conditions

Glioblastoma Multiforme (WHO Grade IV); Anaplastic Astrocytoma (WHO Grade III)

Interventions

06Benzylguanine; MGMT P140K; Meltenyi CliniMacs

Participants

1

Sites

1

Countries

United States

Trials that died the same way

• Effects of Antrodia Cinnamomea on the Hepatoma Patients After Transcatheter Hepatic Artery Chemoembolization
  “poor accrual and insufficient drug supply” (76% match in meaning)
• Biased Opioid Agonists for Treatment of Opioid Withdrawal in OUD
  “Drug availability” (72% match in meaning)
• Deferasirox in Treating Patients With Iron Overload After Undergoing a Donor Stem Cell Transplant
  “Due to slow accrual of patients” (66% match in meaning)
• Efficacy and Safety Study of Cetuximab or Cetuximab Plus Docetaxel to Treat Prostate Cancer Before Prostatectomy
  “lack of patient population - slow accrual” (65% match in meaning)
• Mometasone-furoate for Treatment of Eosinophilic Esophagitis - a Randomized Placebo Controlled Study.
  “Combination slow recruitment, short shelf life for placebo and insufficient funding for further drug production (probably anyway sufficient number included).” (64% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.