Autopsy report · NCT00234468

Iressa vs Placebo as Maintenance Therapy in Locally Advanced NSCLC

“Closed due to insufficient recruitment”

The sponsor’s own words in the registry.

Life of this trial

• Registered 1 year 9 months after it had already started.
• Ran for about 3 years 7 months before it stopped.
• 490 participants planned (an estimate, not an actual count).
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 3

Sponsor

AstraZeneca

Sponsor type

Industry

Conditions

Non Small Cell Lung Carcinoma

Interventions

Iressa (Gefitinib)

Participants

490 (planned, not actual)

Sites

32

Countries

Italy

Trials that died the same way

• Triple vs High Dose Inhaled CORticosteroids
  “The study is closed due to lack of recruitment.” (77% match in meaning)
• Study of Fish Oil to Reduce ALT Levels in Adolescents
  “Study closed for slow recruitment” (75% match in meaning)
• A Pilot Trial of Sonoelastography for Planning Tumor-targeted Prostate Biopsy
  “Insufficient recruitment” (74% match in meaning)
• Prospective Study of Non-operative Management of SBO Without Nasogastric Tube Placement
  “Study was closed due to lack of personnel for recruitment/enrollment purposes.” (72% match in meaning)
• Influence of Dexmedetomidine or Propofol on ICU Delirium
  “insufficient recruitment over a long period” (72% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.