Autopsy report · NCT00201656

Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM)

“This trial was terminated following a futility analysis confirming futility of continuing the study”

The sponsor’s own words in the registry.

Life of this trial

• Registered 10 months after it had already started.
• Ran for about 9 years 5 months before it stopped.
• 58 participants enrolled.
• No results are posted on the registry.

Vital statistics

Status

Terminated

Phase

Phase 4

Sponsor

Obstetrix Medical Group

Sponsor type

Industry

Conditions

Fetal Membranes, Premature Rupture

Interventions

Retention of Cerclage; Removal of Cerclage; Removal vs. Retention of Cervical Cerclage

Participants

58

Sites

23

Countries

United States

Trials that died the same way

• Minocycline for the Treatment of Decreased Mental Function in HIV-Infected Adults
  “This study was terminated early due to futility.” (87% match in meaning)
• Trial to Evaluate UltraSound in the Treatment of Tibial Fractures
  “Study was terminated due to futility” (85% match in meaning)
• Folate Receptor Alpha Peptide Vaccine With GM-CSF Versus GM-CSF Alone in Patients With Platinum Sensitive Ovarian Cancer
  “Futility analysis did not support continuation of the trial” (83% match in meaning)
• Study of Nintedanib and Chemotherapy for Advanced Pancreatic Cancer
  “The study was terminated due to futility and lack of future funding” (81% match in meaning)
• Tissue Adhesive vs. Sterile Strips After Cesarean Delivery
  “Based on results of an interim analysis, the study was halted for futility” (81% match in meaning)

Look deeper

• The official registry record (the source of truth)
• Record history: every change the sponsor made
• Open it in the database

Everything here comes from the current ClinicalTrials.gov record. The timeline uses the record’s dates; dates marked planned are the sponsor’s plans. The cause of death is an automatic, unverified label. This is research information, not medical advice.